ABSTRACT
Objectives: Cytomegalovirus (CMV) colitis is generally diagnosed in immunocompromised patients. It is rare for patients who are not immunocompromised to develop CMV colitis. Cases of CMV colitis in patients with inflammatory bowel disease have also been reported. We encountered a case of CMV colitis with a new diagnosis of severe ulcerative colitis and demonstrated the importance of suspecting ulcerative colitis in immunocompetent patients with CMV colitis.Patient: A 78-year-old woman was hospitalized with fever and diarrhea that had lasted for a month. Colonoscopy revealed continuous diffuse edema, mucosal redness, and multiple punched-out ulcers with bleeding, suggesting cytomegalovirus (CMV) colitis, although she was not immunocompromised. Immunohistochemical staining revealed CMV-positive cells, and CMV colitis was diagnosed. One month later, a colonoscopy was conducted owing to persistent symptoms despite initiating the prescribed antiviral drug. A complete loss of vascular pattern, easy bleeding of the crude mucosa, and exacerbation of multiple punched-out ulcers were observed. She was diagnosed with severe ulcerative colitis. The symptoms of ulcerative colitis disappeared with prednisolone and 5-amino salicylic acid treatment.Conclusion: Ulcerative colitis should be suspected in immunocompetent patients with CMV colitis.
ABSTRACT
Introduction: There is an increasing number of reports demonstrating that dietary small bowel obstruction caused by rice cake consumption can be treated conservatively. However, the course of conservative treatment and the characteristics of the cases that require surgery remain unclear. The purpose of this study was to clarify the clinical features of small bowel obstruction caused by rice cake consumption and the characteristics of cases that require surgery.Methods: We retrospectively assessed all cases of intestinal obstruction caused by rice cake consumption treated at a single institution over a period of 7 years. We also assessed similar previously reported cases.Results: We assessed nine cases in our study and reviewed 67 previously reported cases. Conservative treatment was employed in 56 cases (73.7%). Dietary small bowel obstruction caused by rice cake consumption occurred 1.7 ± 0.3 days after intake. The computed tomography (CT) value of rice cake in the intestine was 160.0 ± 8.9 Hounsfield Units. Pieces of rice cake (length ≥ 4 cm) were observed in five of six cases in which rice cake consumption caused intestinal perforation.Conclusion: In most cases, patients with dietary small bowel obstruction caused by rice cake consumption will recover after conservative treatment. However, there is a high risk of intestinal perforation if intestinal CT reveals the length of rice cake pieces to be 4 cm or longer.
ABSTRACT
Objective: Poor R wave progression in right precordial leads is a relatively common electrocardiogram (ECG) finding that indicates possible prior anterior myocardial infarction (MI); however, it is observed frequently in apparently normal individuals. In contrast, reversed R wave progression (RRWP) may be more specific to cardiac disorders; however, the significance of RRWP in daily clinical practice is unknown. The purpose of this study was to clarify the significance of RRWP in clinical practice.Materials and Methods: We analyzed consecutive ECGs obtained from 12,139 patients aged ≥20 years at Mito Kyodo General Hospital in Ibaraki between November 2009 and August 2012. Our setting is a secondary emergency hospital in the community, and the study participants were inpatients or patients who visited the general or emergency outpatient departments. RRWP was defined as RV2 < RV1, RV3 < RV2, or RV4 < RV3. Regarding ECGs considered to show RRWP, we confirmed the presence or absence of an abnormal Q wave and whether ultrasound cardiography, contrast-enhanced computed tomography, coronary angiography, and/or left ventriculography were performed to obtain detailed information.Results: RRWP was identified in 34 patients (0.3%). Among these patients, 29 (85%) had undergone cardiac evaluation. The final diagnosis was previous anterior MI in 12 patients (41%) and ischemic heart disease (IHD) without MI in 5 patients (17%). All 17 patients with IHD had left anterior descending (LAD) artery stenosis. The other patients were diagnosed with dilated (two patients, 7%) and hypertrophic (one patient, 3%) cardiomyopathy, left ventricular hypertrophy (one patient, 3%), or pulmonary embolism (one patient, 3%). Only seven patients (24%) were normal.Conclusions: RRWP is rare in daily clinical practice; however, it is a highly indicative marker for cardiac disease, particularly IHD with LAD artery stenosis.